Abortion Pill Reversal: What It Is & Why This Information Matters
December 20, 2025
If you’ve taken the first pill of a medication abortion and immediately feel regret or uncertainty, you’re not alone. Many women often feel conflicted or overwhelmed in the moments after taking mifepristone (the first pill of the abortion pill process). Recent studies have also found health risks involved with the Abortion Pill – if you are interested in learning more about this, click here.
The good news? There may still be hope.
It’s called the Abortion Pill Reversal (APR), and it may offer a second chance.
What is the Abortion Pill Reversal?
Abortion Pill Reversal (APR) is a medical protocol designed to counteract the effects of the first abortion pill, mifepristone, using doses of progesterone, a hormone the body naturally produces during pregnancy.
The role of mifepristone is to block progesterone,1 and the APR works by supplying additional progesterone to help restore the conditions needed to support pregnancy.2
Progesterone has been safely used in pregnancy care for decades, including in cases of miscarriage risk.
How Does APR Work?
The APR process typically involves:
- Taking high doses of progesteroneorally, by injection, or by vaginal suppository.
- Beginning treatment as soon as possible, ideally within the first 24 hours.
- Follow-up ultrasoundsto evaluate progress and ensure safety.
Real-world outcomes show that many pregnancies have continued after attempted chemical abortion when APR was started quickly.2
Is APR Safe?
Progesterone has been widely used in obstetrics for:
- Preventing miscarriages
- Supporting IVF pregnancies
- Correcting hormonal deficiencies
Its safety profile is well documented in medical literature.3 The APR protocol is administered by licensed providers, and patients receive ongoing support and monitoring.2
How to Access APR Immediately
If you or someone you know has taken the first abortion pill and wants to reverse it, call:
📞 Abortion Pill Reversal Hotline: 877-558-0333
This hotline is part of the Abortion Pill Rescue Network, which connects women to trained providers 24/7.
Amnion can also help connect you with support, information, and compassionate care. Note: Amnion does not operate 24/7 and recommends that you first contact the APR hotline if you are in need of the Abortion Pill Reversal.
A Message of Hope
Changing your mind is human and feeling overwhelmed is normal. You deserve compassion, support, and real information.
We’re here for you!
📞 Call us at 610.622.9957
📧 Email: info@amnion.org
📍 Or schedule a free appointment on our website: amnionpregnancycenter.com
Sources:
1. FDA – “Questions and Answers on Mifepristone for Medical Termination of Pregnancy Through Ten Weeks Gestation.” https://www.fda.gov/drugs/postmarket-drug-safety-information-patients-and-providers/questions-and-answers-mifepristone-medical-termination-pregnancy-through-ten-weeks-gestation
2. Abortion Pill Rescue Network / Heartbeat International. https://www.heartbeatinternational.org/our-work/apr
3. National Institute of Health – ”Progesterone in Pregnancy: Evidence-Based Strategies to Reduce Miscarriage and Enhance Assisted Reproductive Technology.” https://pmc.ncbi.nlm.nih.gov/articles/PMC10929293/